Discovery and Validation of Orphan Noncoding RNA Profiles across Multiple Cancers in TCGA and Two Independent Cohorts
Our goals with this study were:
Identify and validate novel oncRNAs in six different cancer sites in 10,963 samples (7,942 cancer and 3,021 normal samples) across three large independent cohorts to create the largest known library of oncRNAs.
Develop and validate an artificial intelligence-based (AI) approach to predict cancer tissue-of-origin by leveraging oncRNA expression profiles.
